Pre-Exposure Prophylaxis (PrEP)

TRUVADA for PrEP (pre-exposure prophylaxis) is a prescription medicine that can help reduce the risk of getting HIV-1 through sex, when taken every day and used together with safer sex practices. This use is only for people who weigh at least 77 pounds and are HIV-negative and at risk of getting HIV-1.

Post-Exposure Prophylaxis (PEP)

Key Points

  • Post-exposure prophylaxis (PEP) involves taking HIV medicines very soon after a possible exposure to HIV to prevent becoming infected with HIV.
  • PEP is intended for emergency situations. It is not meant for regular use by people who may be exposed to HIV frequently.
  • PEP must be started as soon as possible to be effective and always within 72 hours (3 days) after a possible exposure to HIV.
  • PEP involves taking HIV medicines every day for 28 days.